Acute and chronic pain often affects our companion animals, such as dogs, cats and horses. Available options for pain relief for animals are even more limited than for humans, and many common painkillers are not well tolerated by animals. Unfortunately, some pain conditions that affect animals are so excruciating that they can lead them to fall severely ill. Sometimes, animals have to be put down because of their unrelieved pain and the lack of available treatments.
At EicOsis we have been working for more than a decade to provide hope to animals in pain and their human caregivers. EC1728 is our first drug candidate developed specifically for animals.
EC1728 relieves pain in companion animals including horses.
EC1728 is a soluble Epoxide Hydrolase (sEH) inhibitor developed for use in companion animals to relieve pain. Results show that EC1728 is safe and efficacious in dogs with arthritis. Studies in horses with chronic pain show EC1728 relieves chronic pain resulting from laminitis. Horses with laminitis, a disease that is estimated to be up to 70% fatal in severe cases, suffer from severe inflammation of the hoof that leads to intense pain, tissue destruction, and severe hypertension. Initial studies with EC1728 show that it is safe and efficacious in horses. EicOsis is undergoing clinical trials in horses in 2019.
Investigational New Animal Drug (INAD) for EC1728 as an Analgesic for Animals submitted in 2019
EicOsis has filed an application to begin safety testing of EC1728 in animals.